abstract |
7 - [[1.alpha., 5.alpha., 6.alpha.] - 6-amino-3-azabicyclo [3.1.0] -hex-3-yl] -6-fluoro-1- (2) salt, 4-difluorophenyl / -1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid and methanesulfonic acid, which contains the following major peaks in the X-ray powder diffraction pattern: peak 1: 2 theta /.degree C / Cu 4.5, distance d 19.5; peak # 2: 2 theta /.degree.C/ Cu 7.7, distance d 11.5; peak # 3: 2 theta /.degree.C/ Cu 9.1, distance d 9.7; peak # 4: 2 theta /.degree.C/ Cu 13.6, distance d 6.5; peak # 5: 2 theta /.degree.C/ Cu 15.0, distance d 5.9; peak # 6: 2 theta /.degree.C/ Cu 18.2, distance d 4.9; peak # 7: 2 theta /.degree.C/ Cu 18.6, distance d 4.8; peak # 8: 2 theta / Congestion Cu / Cu 22.8, distance d 3.9 exhibits advantageous stability so that it is suitable for the manufacture of antibacterial pharmaceutical compositions. This salt is produced from the corresponding salt, which does not exhibit the above characteristics , or a monohydrate thereof, by heating in the presence of an alcohol or a mixture thereof with an aprotic corrosion |