| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad3d51747a2eba1e7636894263252df4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate |
1993-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfadd05de63aa7a0da6361f367aa321a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27059208b0c36feb2b6db8bcbcb81f05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74e93cbfb700a651ce1afa826da62bfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86858cc7dcca65a2b2ac8812316f83cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ed4ed625d728caf4d35806eaaa9dbcd |
| publicationDate |
1997-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-282447-B6 |
| titleOfInvention |
A method for producing cefriaxone disodium hemiheptahydrate |
| abstract |
A new and improved process for producing the ceftriaxone disodium hemiheptahydrate of formula I wherein the disodium salt is 7-amino-3- (2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazine-3-yl) thio / methyl-3-cephem-4-carboxylic acid is reacted with a reactive derivative of 2- (2-aminothiazol-4-yl) -2-syn-methoxyiminoacetic acid, such as 2-benzothiazolyl-thioester, in aqueous solution and with the desirability of an inert organic solvent such as acetone at a temperature between about 0 to about 40 ° C, after which the desired compound is isolated in a very pure form and a high total yield. Ceftriachon is a third generation cephalosporin antibiotic for parenteral use and a valuable agent for the treatment of infections. |
| priorityDate |
1992-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |