http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-267699-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 |
| filingDate | 1998-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bd98991270cd6e5b1c68807ed6e27cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_140c4217bbef66f36ee7dca5aa461530 |
| publicationDate | 2000-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-267699-A3 |
| titleOfInvention | Arylsulfonylamino Hydroxamic Acid Derivatives, Pharmaceutical Composition, Method for inhibiting Matrix Metalloproteinase or Production of Tumor Necrosis Factor and Method of Treatment |
| abstract | Derivatives of arylsulfonylaminohydroxamic acidnof Formula I are inhibitors of matrix metalloprotein orntumor necrosis factor production and are useful in treatmentnconditions selected from arthritis, cancer,ntissue ulceration, restenosis, periodontal disease,nepidermolysis bullosa, scleritis and other diseasesncharacterized by the activity of matrix metalloproteinase as well asnAIDS, sepsis, septic shock and other diseases involving productionnTNF. In addition, these compounds can be used in the followingncombination therapy with standard non-steroidal therapiesnanti-inflammatory drugs (NSAIDs) and analgesics for treatmentnarthritis and further in combination with cytotoxic drugs such asnadriamycin, daunomycin, cis-platinum, etoposide, taxol, taxotere andnalkaloids such as vincristine in the treatment of cancer. |
| priorityDate | 1998-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.