| abstract |
Nanofibrous material especially for topical use in therapies consisting of a lipophosphonoxin group of formula I, wherein R 1 is (C 8 -C 22) alkyl, hexadecyloxypropyl, tetradecyloxypropyl, tetradecyloxyethyl or hexadecyloxyethyl, R 2 is uracil, thymine or cytosine, and R 3 is primary, secondary or tertiary amine, diastereomers and mixtures of diastereomers of compounds of formula I and their pharmaceutically acceptable salts and hydrates, incorporated into polyester-based nanofibers of formula II, wherein m is at least 1, and R is -H or (C1-C10) alkyl, or its copolymers. |