http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2015574-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae288c85af7a35c8f652262fae4bd3e2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 |
| filingDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c9f5391555f8a25ea8bd555200ba629 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc0f22a66a3fba7da3dad87da66616d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a68fa7af7d8ac340264c171014d6f846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d264aa9a27c5004f472ff6484612a7ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94a8b4268046ed0c09e909639415a33a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eebcb3910bb1efbc7c53a48bb5b77fae |
| publicationDate | 2017-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-2015574-A3 |
| titleOfInvention | Hydrophobized ester derivatives of hyaluronic acid or their salts, process for their preparation, nanomicellar composition, process for their preparation and use |
| abstract | The present invention relates to hydrophobized ester derivatives of hyaluronic acid containing alkylaryl or alkylheteroaryl substituents of the general formula I wherein R 1 is H or a table thereof. -CO (CH.sub.2.n) C.sub.6.nHsub.4-p .nRsup.5.n.or -CO-C.sub.6.nHsub.4-p .nO (CH.sub.2.n.), Sub.ynCH.sub.3.n., Or -CO- (CH.sub.2.n.). Sub.znNC.sub.12.nHsub. 8.n. where R.sup.5 is H or CH.sub.3; x is an integer ranging from 4 to 21, preferably from 4 to 15, or y is an integer from 8 to 21, preferably from 8 to 15, or z is an integer from 3 to 16, preferably from 7 to 11, most preferably from 10 to ; and - (CH.sub.2.n.) sub.x-.n.or - (CH.sub.2.n.) sub.y-.n.or - (CH.sub.2.n is a linear saturated or unsaturated part of the chain, wherein at least one repeating unit is one or more or -CO (CH.sub.2.) sub.xnCsub.6. nHsub.4.n..sub.-p .nRsup.5.n.or -CO-C.sub.6.nHsub.4-p .nO (CH.sub.2.n.) sub or -CO- (CH.sub.2.n.) sub.NC.sub.12.nHsub.8.n; R 3 is H or R 5 is 2; and wherein n is an integer ranging from 1 to 495 dimers. The invention further relates to a process for their preparation and their use for encapsulation of biologically active water-insoluble aromatics to form a nanomicellar composition which is then used for pharmaceutical and cosmetic applications. |
| priorityDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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