http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-201497-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-86 |
filingDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9082ac318f6001ef1e64eb1626e62f20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2724e119a2d3b76be44db231da2541e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a09e783a8030514579ebd786794976ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b38ca19f21f151b0cda9bc85650d81b |
publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-201497-A3 |
titleOfInvention | Crystalline forms of enzalutamide |
abstract | The present invention provides novel crystalline forms of enzalutamide, designated as forms 1, 2, 3, and 4. These forms have been characterized by X-ray powder diffraction and 1 H NMR. In all cases, crystallization is understood to mean dissolving enzalutamide at elevated temperature, respectively. at boiling point in a given solvent, gradual gradual cooling of the obtained solution at temperatures of 23 to 27 degC, allowing the mixture to be crystallized at a temperature of 23 to 27 degC, or lower (i.e. 0 degC to about -20 degC) .C), and subsequently isolating the crystals by suction. A minimum solvent / solvent mixture is always used for crystallization, in which the enzalutamide is completely dissolved. |
priorityDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.