http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2014757-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3ea88a5a4aa2565217643bc46a885f6d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 |
| filingDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bff3a7323a6ff6a22b16404f3b5b890 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe5c4ab15a100ba3aa9d1b91b8896bfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fbb88c1d6a3f8b638baec2ed64bafb9 |
| publicationDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-2014757-A3 |
| titleOfInvention | Polymer substrates for direct covalent binding of biomolecules |
| abstract | The subject of the solution are polymer substrates allowing direct covalent binding of biomolecules while maintaining their biofunctional properties. Polymer substrates are prepared by a process based on the activation of their surfaces by atmospheric plasma in the air followed by binding of the desired biomolecules. The covalent attachment of biomolecules was verified by the example of polytetrafluoroethylene (PTFE), to which bovine serum albumin was covalently bound. The preservation of biofunctional properties of bound biomolecules was verified on the example of tropoleastin bound to a thin polytetrafluoroethylene film, while the bioactivity of tropolestine was verified by the study of endothelial cell growth on the surface with tropoelastin. It has been shown that in this case the growth of endothelial cells is significantly faster on the surface of PTFE with covalently bound tropoelastin than in the case of PTFE film without surface activation and without bound tropoelastin. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021069691-A1 |
| priorityDate | 2014-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.