Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6df885157441d009872c020ab4a1d203 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B43-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B43-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-182 |
filingDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aff1d5bfdeb5358f1e92c825b9bc806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51ef31320edad0b45b74d8679693e74d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4524ec5a233ac9f4652ec7f638b4032b |
publicationDate |
2013-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-2011847-A3 |
titleOfInvention |
Method of direct mono-N-substitution of piperazine |
abstract |
The present invention provides a process for the direct mono-N-substitution of piperazine in synthetically significant yields in a simple embodiment, wherein the piperazine-1-ion cation is prepared and the piperazine-1-cation reacts with the electrophilic agent, preferably with a d-metal compound. at a molar ratio of piperazin-1-cation to electrophilic reagent in the range of 1: 1 to 1: 1.4. |
priorityDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |