http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2009763-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2009-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ba19c3ee4da971b4ecfe53d9915ae4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cecda45bf389f6bb1ddad2ce7533260 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a49bbd7d49323cb73fe386b78ebadcda |
| publicationDate | 2011-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-2009763-A3 |
| titleOfInvention | A method for producing highly purified 5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] -4,5,6,7-tetrahydrothieno [3,2-c] pyridin-2-yl acetate known under the unprotected name prasugrel and its new pharmaceutically acceptable salts. |
| abstract | The process for preparing 5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] -4,5,6,7-tetrahydrothieno [3,2-c] pyridin-2-yl acetate of formula I or a salt thereof having wherein the compound of formula (III), which is in the form of a salt with arenesulfonic acid, is reacted with a compound of formula (XV) wherein Y is: chloro, bromo, or an OR group, wherein R is 4. The alkanesulfonic or arenesulfonic acid group, in the organic solvent in the presence of an inorganic base or an organic base, after addition of an acetylating agent and an organic base to the reaction mixture, yields a compound of formula I which crystallizes from the reaction mixture upon addition of the co-solvent. it is converted to the salt by reaction with an organic or inorganic acid in a suitable solvent. |
| priorityDate | 2009-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.