| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate |
2008-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ba19c3ee4da971b4ecfe53d9915ae4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cecda45bf389f6bb1ddad2ce7533260
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_997332c4745a1f1c029dbe26efb20b72 |
| publicationDate |
2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-2008748-A3 |
| titleOfInvention |
A method for producing highly pure 5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] -4,5,6,7-tetrahydrothieno [3,2-c] pyridin-2-yl acetate, prasugrel |
| abstract |
Preparation of prasugrel by a process using 3-cyclopropyl-1- (2-fluorophenyl) -3-oxopropyl methanesulfonate to alkylate 2-oxothienotetrahydropyridine, which may be in the form of a salt, for example with hydrochloric acid or p-toluenesulfonic acid. The resulting compound of formula II is then acylated directly with the acetic anhydride in the reaction mixture without isolation and the resulting prasugrel of formula I is then crystallized directly from the reaction mixture. |
| priorityDate |
2008-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |