| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 |
| filingDate |
2007-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ba19c3ee4da971b4ecfe53d9915ae4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cecda45bf389f6bb1ddad2ce7533260 |
| publicationDate |
2009-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-2007456-A3 |
| titleOfInvention |
The method for producing 5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] -4,6,6,7-tetrahydrothieno [3,2-c] pyridin-2-yl acetate (prasugrel) |
| abstract |
A process for the preparation of 5- [2-cyclopropyl-1- (2-fluorophenyl) -2-oxoethyl] -4,5,6,7-tetrahydrothieno [3,2-c] pyridin-2-yl acetate of formula (I) wherein the compound of formula (VI) is reacted with a cyclopropylmagnesium halide to form a compound of formula (V) which is further reacted with methanesulfonyl chloride to form a methanesulfonate of formula (IV) which is further converted to a compound of formula (II) by reaction with a compound of formula (III) and converted into a substance by acetylation reagent of formula I. |
| priorityDate |
2007-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |