http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2005510-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-12 |
| filingDate | 2005-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ba19c3ee4da971b4ecfe53d9915ae4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_515f41a91eb18042611033ccbac1ae97 |
| publicationDate | 2007-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-2005510-A3 |
| titleOfInvention | Method of producing (S) -3- (aminomethyl) -5-methylhexanoic acid (pregabalin) |
| abstract | A method for the preparation of a 3-aminomethyl-5-methylhexanoic acid derivative of formula A, in particular an optically pure form of formula A ', wherein X is H.sup.2, alkali metal or alkaline earth metal, in which case the compound of formula B or its optically the pure form of formula B ', wherein Y is OH or NHR 1, NR 1, NR 2, R 2, OR 1, SR 2. n., where R.sub.1.n. and R.sub.2.n. is C.sub.1.n. az C.sub.20.n. aryl or alkyl; and R.sub.2.n. are part of a carbon cycle of 4 to 5, converted to a compound of formula A (A ') where Y is as defined above by a process involving the catalytic hydrogenation of a cyano group with hydrogen gas in an alkaline environment using a nickel catalyst. |
| priorityDate | 2005-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.