http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2004923-A3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61073c1e31fd071ce34b222022390b02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B11-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D411-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B11-26 |
filingDate | 2004-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2654243cb7f6038726293bf5d925193 |
publicationDate | 2006-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-2004923-A3 |
titleOfInvention | Chemoselective method of monoaminomethylation of sulfophthalein and sulfofluorescein derivatives |
abstract | Aminomethylated sulfophthalenes and sulfofluoresceins are prepared by treating N-alkoxymethylamine, N-aryloxymethylamine, 1-N-benztriazolylmethylamine, N-imidazolylmethylamine, N-1,2,3-triazolylamine, N-1,2,3-triazolylamine, imidyloxymethylamine. acyloxymethylamine, iminomethylamine, aminomethylamine, and methylene ammonium salts to the starting sulfophthaleins of formula I wherein at least one substituent of the group R @ 2, R @ 2, R @ 3, R @ 6, R @ 6, R @ 6. or R.sup.7.n. hydrogen, to the starting sulfofluoresceins of formula (II) wherein at least one substituent of the group R @ 2, R @ 2, R @ 3, R @ 4, R @ 4, R @ 4, R @ 4, R @ 4, R @ 4, R @ 4, R @ 4. and R.sup.5.n. hydrogen, in the environment of protic or aprotic polar solvents at temperatures ranging from 25 to 300 degC. The aminomethylation by this method is highly chemoselective and regioselective. |
priorityDate | 2004-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.