abstract |
Compounds are provided which have the structure: (formula I); wherein Q is C or N; R<2a>, R<2b>, R<2c>, X1 to X7, R<1>, R<2>, R<3>, R<3a>, R<4>, A, Y, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents. The present invention further provides a method for treating obesity and dyslipidemia in mammals including humans through simultaneous inhibition of peroxisome proliferator activated receptor- gamma (PPAR gamma ) and stimulation of peroxisome proliferator activated receptor- alpha (PPAR alpha ). |