| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34fadf00cbf436daf378c00070f76020 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2013 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 |
| filingDate |
2003-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0697beabb0c7f74ee4795f91945d2f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8102337a5c2bf8b589072e69dbff68c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dc24f05079372b8cfae6db0489000d0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ec4241fb5ecde9a782bd3ecab64bf67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9636ece3d551e1aafcc632d644eb6629 |
| publicationDate |
2005-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CZ-20033216-A3 |
| titleOfInvention |
A method for the preparation of an immediate-release oral solid dosage form of an active ingredient comprising as active ingredient a polymorphic form of finasteride |
| abstract |
A method of preparation of an oral solid dosage form with instant release of an active agent containing as the active agent finasteride characterized in that that an aqueous suspension containing 5 % to 50 % by weight of finasteride, based on the total weight of the suspension, and 0.1% to 50 % by weight of at least one anion surfactant, based on the weight of finasteride is milled in order to reach such distribution of particle size of finasteride that the size of 10 % of particles does not exceed 2 µm, the size of 50 % of particles does not exceed 7 µm, and the size of 90 % of particles does not exceed 17 µm, then the obtained aqueous suspension is sprayed to a fluid bed onto a solid particle hydrophilic carrier having such distribution of particle size that the size of 90 % of particles exceeds 40 µm and the size of 10 of particles exceeds 200 µm, and the size of 99 % of particles does not exceed 300 µm. |
| priorityDate |
2003-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |