http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20031812-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_044d942b08a266c72dd037e953ba367c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 |
| filingDate | 2001-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_052148001055845677a89a93131a092c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90c6632d61b37b4684798f4138bef6a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1f629f6fc778df7d795658e504550ce |
| publicationDate | 2004-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20031812-A3 |
| titleOfInvention | Novel quinuclidine derivatives and medicinal compositions containing the same |
| abstract | A compound of formula (I), wherein B is a phenyl ring, a 5 to 10 membered heteroaromatic group containing one or more heteroatoms, or a naphthalenyl, 5, 6, 7, 8- tetrahydronaphthalenyl, benzo[1,3]dioxolyl, or biphenyl group; R1, R2 and R3 each independently represent a hydrogen or halogen atom, or a hydroxy group, a phenyl group, -OR<7>, -SR<7>, -NR<7>R<8>, -NHCOR<7>, -CONR<7>R<8>, -CN, -NO2, -COOR<7> or CF3 group, or a strait or branched, substituted or unsubstituted lower alkyl group, wherein R<7> and R<8> each independently represent a hydrogen atom, a straight or branched lower alkyl group, or together form an alicyclic ring; or R<1> and R<2> together form an aromatic or alicyclic ring or a heterocyclic group. n is an integer from 0 to 4; A represents a group selected from -CH2-, -CH=CR<9>-, -CR<9>=CH-, -CR<9>R<10>-, -CO-, -O-, -S-, -S(O)-, -S(O)2- and NR<9>, wherein R<9> and R<10> each independently represent a hydrogen atom, a straight or branched lower alkyl group, or together form an alicyclic ring; m is an integer from 0 to 8, provided that when m=0, A is not -CH2-; p is an integer from 1 to 2 and the substitution in the azonia bicyclic ring may be in the 2, 3 or 4 position including all possible configurations of the asymmetric carbons; R4 represents a group of structure: (Formulae II) wherein R<11> represents a hydrogen or halogen atom, a hydroxy group, an alkoxy group, a nitro group, a cyano group, -CO2R<12> or -NR<12>R<13>, wherein R<12> and R<13> are identical or different and are selected from hydrogen and straight or branched lower alkyl groups, or a straight or branched, substituted or unsubstituted lower alkyl group; R<5> represents an alkyl group of 1 to 7 carbon atoms, an alkenyl group containing 2 to 7 carbon atoms, or a group of formula (III) wherein q=1 or 2 and R<11> iss a defined above; R<6> represents a hydrogen atom, a hydroxy group, a methyl group or a -CH2OH group; and X<-> represents a pharmaceutically acceptable anion of a mono or polyvalent acid. |
| priorityDate | 2000-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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