| abstract |
The invention relates to formula (1) heterocyclic aminoalkyl pyridine derivatives, whereby R<1> represents the radical of a heterocycle comprising 1 to 3 ring structures which are saturated, unsaturated or aromatic and optionally annellated with other ring structures to form a condensed ring system, and which comprise a total of 1 to 4 N-, O- and/or S-atoms, said heterocycle being optionally substituted once, twice or three times by at least one of the following groups: -A, -OR<4>, -N(R<4>)2, -NO2, -CN, Hal, -COOR<4>, -CON(R<4>)2, -COR<4>, = O; R<2> represents a phenyl group which is optionally substituted once, twice, three, four or five times by at least one of the following groups: Hal, A, -O-A, -NO2 or CN, or a thienyl group which is optionally substituted once or twice by at least one of the following groups: Hal, A, -O-A, -NO2, -CN or thienyl; -X- represents -O-, -S-, sulfinyl, sulfonyl, or -C(R<4>)2-; -Y- represents -[C(R<4>)2]n-; -Z- represents -C(R<4>)2-; and n represents 1, 2, 3 or 4. The invention also relates to the compatible salts and solvates of the heterocyclic aminoalkyl pyridine derivatives and the use thereof as pharmaceuticals. |