abstract |
The invention relates to combinations of one or more antiinflammatory agents and a compound of the formula <CHEM> wherein R<1>, R<2> and R<3> are as defined above, which are are useful therapy as immunosuppressive agents for organ transplants, xeno transplation, lupus, multiple sclerosis, rheumatoid arthritis, psoriasis, Type I diabetes and complications from diabetes, cancer, asthma, atopic dermatitis, autoimmune thyroid disorders, ulcerative colitis, Crohn's disease, Alzheimer's disease, Leukemia and other autoimmune diseases. |