| abstract |
The invention relates to benzoyl derivatives of formula (I) and the physiologically acceptable salts and solvates thereof, wherein R<1>, R<2>, R<3>, R<4>, R<5> and R<6> have the meanings cited in Claim 1. Said derivatives inhibit phosphodiesterase IV and can be used to treat allergic diseases, asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin diseases, inflammatory diseases, auto-immune diseases such as rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumoral growth or tumoral metastases, septicemia, memory defects, atherosclerosis and AIDS. |