Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59 |
filingDate |
1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e2462b245c167cdcac1b99109d39394 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e96a1a0656fd4ba6a922f32729c868 |
publicationDate |
2001-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-20011388-A3 |
titleOfInvention |
Multiple domain glycoprotein hormones and methods for their use |
abstract |
Forms of differentially acting glycoprotein hormones are disclosed. These compositions are of the formula: (1): beta <1>-(linker<1>)m- alpha -(linker<2>)n- beta <2>; (2): beta <1>-(linker<1>)m- beta <2>-(linker<2>)n- alpha ; (3): alpha -(linker<1>)m- beta <1>-(linker<2>)n- beta <2>; (4): beta <2> APPROX alpha -(linker)m- beta <1>; or (5): beta <1>-(linker)m- alpha APPROX beta <2> wherein each of beta <1> and beta <2> has the amino acid sequence of the beta subunit of a vertebrate glycoprotein hormone or a variant of said amino acid sequence, as variants are defined herein. " alpha " designates the alpha subunit of a vertebrate glycoprotein hormone or a variant thereof; "linker" refers to a covalently linked moiety that spaces the beta <1> and beta <2> subunits at appropriate distances from the alpha subunit and from each other. " APPROX " is a noncovalent link. Each of m and n is independently 0 or 1. |
priorityDate |
1998-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |