http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2000946-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 |
| filingDate | 1998-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c3206570fb2f98aefe317f16dffa9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb3eb240aa1177953641ddd7fcc7c22c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3adce6ca41606275d7e722fe361fc005 |
| publicationDate | 2000-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-2000946-A3 |
| titleOfInvention | A combination of a 5-HT uptake inhibitor and a h5-HT1B antagonist or partial agonist |
| abstract | This solution relates to the combination of the first component (a) beingna 5-HTa-inhibitor of the second component (b)nh5-HT1B selective antagonist or partial agonistnof formula (I) wherein X is CH 2, oxygen,nY is CONH, NHCO, R 1 is hydrogen, C 1 -C 6nan alkyl group, a C 1 -C 6 cycloalkyl group, R 2 is an atomnhydrogen, C 1 -C 6 alkyl, C 1 -C 4 alkoxy, atomnhalogen, R 3 is (1), (2), (3), (4) CF 3, R 4 and R 5 arenâ– ** independently of one another a hydrogen atom or a C 1 -C 4 alkyl groupnin the form of the racemate, the R-enantiomer or the S-enantiomer and thesenthe components (a) and (b) are in the form of free bases, solvates orntheir pharmaceutically acceptable salts, their preparation,npharmaceutical compositions containing these combinations,nuse and method of treating affective disorders such as depressionnanxiety and obsessive compulsive disorder with this combination as wellnsuch as kits comprising the combination. |
| priorityDate | 1998-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 257.