| abstract |
A new process for producing 13,14-dihydroprostaglandin derivativesnA E and F with the use of non-methyl 7 - (- hydroxy-5- (2- (2-noxiranyl) ethyl) -4- (1,2,2,2-tetrainethylsilapropoxy) cyclopentylnheptanoate intermediatesncan be synthesized from commercially available methyl 7- [3- (nR) -hydroxy-5-oxo-1-cyclopent-1-yl] heptanoate. Newnthe intermediate may react with various oxygenated simsnwith both carbon and nitrogen nucleophiles to form the abovenprostaglandin derivatives, the preparation being shorter andncompared to the methods described |