http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-2000761-A3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07b71571160c289fbf5fc680dfea513f |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate | 1998-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54ffd867065e8d8157cfaded10c832b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d49a5c5d7768dafe8ef4272198383b82 |
publicationDate | 2000-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-2000761-A3 |
titleOfInvention | IL-8 receptor antagonist |
abstract | The present invention relates to novel spiro compounds of the formula I and their compoundsncompositions suitable for the treatment of disease states that arenchemokine, interleukin 8 (11 ^ 8).nPreferred compounds of formula I are those in which R 1 isn-NH-C (X) -N- (CR 13 R 14) v-Z; Z is optionally substitutednnaphthyl, optionally substituted heteroaryl, optionallynsubstituted ω 6 () alkyl, optionally substituted C 1-10 alkenylnOr optionally substituted C 1-10 alkynyl; X is = O or = S; ANDnis the carbon that is contained in the 3 to 7 membered spiral, wherenthis ring may optionally contain a heteroatom selected fromn* HIM WITH; v is 0 or an integer having a value of 1 to 4; ornpharmaceutically acceptable salts thereof. |
priorityDate | 1998-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 289.