http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20004214-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f4dfbf7e928b2477534a09534993e7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 |
| filingDate | 1999-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f34c4827d52dd4ac9c2b14365558f8c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e55ee07954b136fcbbcccf170e1c520c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6579d2f9703a92ce5956ca5eafec974 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b3163171955aa527e2c908567b26770 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623bba2cdeda0461add1705051e57e96 |
| publicationDate | 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20004214-A3 |
| titleOfInvention | Soluble T cell receptor |
| abstract | The present invention relates to a recombinant soluble T receptorncells. The T cell receptor (TCR) is folded into the correct onenspatial arrangement and contains recombinantnthe extracellular domain of α or g of the TCR chain having the firstnheterologous C-terminal dimerization peptide, and recombinantnthe extracellular domain of b or d of the TCR chain having a secondna heterologous C-terminal dimerization peptide that is specificallynheterodimerized with the first dimerization peptide, songenerates a heterodimerization domain, which may be a domainnwith the coil coil conformation. The solution further provides sequencesnnucleic acids encoding recombinant TCR and methodnpreparing recombinant TCRs. TCRs may be labeledna detectable label so that they can detect specificnMLIC-peptide complexes. Alternatively, they may benlinked to a teape agent such as cytotoxicnor immunostimulating the agent to transfer the agent toninstead of a specific MHC-peptide complex. |
| priorityDate | 1999-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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