http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20004210-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_777ddbb5fae24e6edef995ed66ff4c95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d4e15284299e30d03828fc3e1387e19 |
| publicationDate | 2001-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20004210-A3 |
| titleOfInvention | Benzamide derivatives for the treatment of cytokine mediated disease |
| abstract | Amide derivatives of formula I wherein R 3 is (1-6C) alkyl or halogen, m is 1-3 and R 1 is selected from: (A) hydroxy, halogen, (1-6C) alkyl , (1-6C) -alkoxy, aryl, heteroaryl and heterocyclyl, and (B) di [(1-6C) alkyl] -amino- (1-6C) alkyl, (1-6C) alkoxy - (2-6C) alkoxy- (2-6C) alkoxy, di - [(1-6C) alkyl] amino- (2-6C) alkoxy, aryloxy, heteroaryloxy, heteroaryl- (1 -6C) alkoxy, heterocycloxy, heterocyclyl- (1-6C) alkoxy, p represents 0-2 and R2 represents a group such as hydroxy and halogen, q represents 0 to 4; R 4 represents an aryl or cycloalkyl group carrying 1 to 3 substituents such as: (C) hydrogen, hydroxy, halogen and heterocyclyl, and (D) heteroaryl- (1-6C) alkoxy and heterocyclyl- (1- 6C) alkoxy with the proviso that the substituent on R 4 is selected from (C) only when at least one R 1 is selected from (B). Further disclosed are methods for their preparation, pharmaceutical compositions comprising said derivatives, and the use of such derivatives in the treatment of diseases or medical conditions mediated by cytokines. |
| priorityDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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