abstract |
The novel steroid derivative compounds of the formula I,nwherein the individual substituents are as defined in claim 1,nfor example, 4,4-dimethylcholest-8,14,25-trien-3β-ol may benused to stimulate meiosis in vitro, in vivo or ex vivo.nThese compounds may be agonists naturallynmeiosis-activating substances, and can therefore benused to treat infertility in females and males, preferably in femalesnand men when infertility is the result of insufficient stimulationngerm cell meiosis. In other cases it may benthe regulation of meiosis by the claimed compounds useful innin vitro or ex vivo, or vice versancontraceptive action. |