http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20004071-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44367c7b17bf07d2d403f117a3fe1a97 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 1999-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5febe78a71b9d37b0e8cef0cc7ef54aa |
| publicationDate | 2001-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20004071-A3 |
| titleOfInvention | Benzofuroxane derivatives and their use in the treatment of angina pectoris |
| abstract | The solution describes novel benzofuroxane derivatives of the general formulanof formula I wherein R is -O- (CH 2) n -X-R ', η = 1 to 6, X is -NHC (O) -,noxygen or a bond, R 'is a lower alkyl group C 1 to C 8,nan aromatic, heteroaromatic, sub-substituted residuenor unsubstituted saturated heterocyclic ring snone or two heteroatoms such as nitrogen or oxygen,nwherein the substitution is lower alkyl or R is selectednfrom the groups a, b, c, d, e, wherein R "is hydrogen, nitro, lowernalkyl or -C (O) -R '', wherein R "'is hydrogen,na lower alkyl group or an aryl group thereof;npharmaceutically acceptable salts. The following describes the preparation methodnderivatives of formula (I), use as defined abovenderivatives of formula I as NO donors and / orncoronary heart disease and pharmaceutical preparationsncontaining derivatives of formula I as active ingredients.nThe invention also describes a method of treating coronary diseasesnheart by administering an effective amount as defined abovenof the general formula (I). |
| priorityDate | 1999-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.