http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20004026-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D273-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C257-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155 |
| filingDate | 1999-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be3537011c599307a45f266b76f4e4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1e9078a30d1e5c0ccf05ea611776a71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34af450328dd7d686e4081d0dab88740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5438d66728d315a132cf015ba308b48a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7907a934850f6cb1ca85e5c3f93dc333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_020aaa95fa2e077311482849bdb27c3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d785e20b829a349567587e5f70ab6b2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1eac882e27f0f0e850ad2d25aecd8421 |
| publicationDate | 2001-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20004026-A3 |
| titleOfInvention | A biphenyl derivative, a process for its preparation, its use and a pharmaceutical composition containing it |
| abstract | The biphenyl-general derivative of formula (I) wherein R 1, R 4 are denoted bynindependently, -C (= NH), NH2 optionally substitutednone -COA, -CO- [C (R 6) 2] - Ar, -COOA, -OH, ornthe usual amino protecting group or NHC (= NH) -NH 2,n-CO-N = C (NH 2) 2, a group of formula (a) or (b),nR 2, R 3, R 5 are independently hydrogen, A,n, OR 6, N (R 6) 2, NO 2, CN, Hal, NHCOA, NHCOAr, NHSO 2A,nNHSO2Ar, COOR6, CON (R6) 2, CONHAr. COR6, COAr,nS (O) A S (O) "Ar, -O- [C (R 6) 2] m -COOR 6, - [C (R 6) 2] D-COOR 6, -nO- [C (R 6) 2] m-CON (R 6) 2 - [C (R 6) 2] -CON (R 6) 2 -O- [C 1-6] z -MONONrnor - [C (R6) 2] p-CONHar, X is - [C (R6) 2] n, -nCR6 = CR6-, - [C (R6) 2] n-O-, -O- [C (R6) 2] n-, -COo, -OOC-, -nCONR 6 - or -NR 6 CO-, R 6 represents hydrogen, A or benzyl, Anis C 1-20 alkyl, wherein 1 or 2 -CH 2 -s arenoptionally replaced by an O or S atom or groups -nCR 6 = CR 6 - and / or 1 to 7 hydrogen atoms are replacednfluorine, Ar is phenyl or naphthyl optionallynsubstituted with 1, 2 or 3 groups of A, Ar, Or6,nOAr ', N (R6) 2, NO2, CH, Hal, NHCOA, NHCOAr', NHSO2A,nNHSO2Ar ', COOR6, CON (R6) 2, CONHAr', COR6, COAr ',nS (O) "A and S (O)" Ar ', Ar' represents phenyl or naphthyl optionallynsubstituted with 1, 2 or 3 groups from the group A, OR 6,nN (R 6) 2, NO 2, CN, Hal, NHCOA, COOR 6, CON (R 6) 2, COR 6 andnS (O) nA, Hal is F, Cl, Br or J, n is 0, 1 or 2,nmaps are always 1 or 2, and their salts are as suchnFactor Xa coagulation inhibitors suitable for productionnpharmaceutical compositions for treatment and preventionnthromboembolic diseases. |
| priorityDate | 1999-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 179.