http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20003558-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da767cbc78bb3714342864c20e36af4b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-28 |
| filingDate | 2000-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9558df85191592c38c075a9971436e35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0e1c022ce6da620b1fa0d003527a63d |
| publicationDate | 2002-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20003558-A3 |
| titleOfInvention | Process for preparing (-) - N-cyclobutylmethyl-14β-hydroxy-3-methoxymorphinan |
| abstract | In the present invention, there is disclosed a novel one-stage synthesis process of (-)-N-cyclobutylmethyl-14{beta}-hydroxy-3-methoxymorfinate (cycloamine) of the structural formula I, a precursor for preparing a strong morphinane analgesic known as butorphanol. The invented synthesis comprises a sequence of several reaction steps being carried out in one apparatus and without isolation and purification of intermediates. By execution of the said sequence of the reaction steps a substance of the structural formula I is prepared from the starting (+)-1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112592342-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112592342-A |
| priorityDate | 2000-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.