http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-20003111-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb66d9373d09efad73c142762f6dfb00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate | 1999-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5b4ce6cfa7a5c1fe7fff6478ce25e5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dc16697ad07bcdee5dd802baedd4b23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f12e79d30f8c4efbf4db4048c68db278 |
| publicationDate | 2001-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-20003111-A3 |
| titleOfInvention | Self-Regulatory Apoptosis of Inflammatory Cells by Gene Therapy |
| abstract | Chimeric nucleic acids and therapeutic are disclosedninduction of apoptosis in activated inflammatory cells;ncells at the site of inflammation by introduction into these cellsnchimeric nucleic acid. Chimeric nucleic acidnhas at least one TNFα promoter enhancer attached tona copy of the TNFα promoter and further attached at least tonone copy of the apoptosis-inducing gene which is further attachednto 3'UTR. The apoptosis-inducing gene is granzym B. Solutionnfurther relates to methods for preparing and using chimericnnucleic acids suitable for self-regulation of apoptosis anpharmaceutical compositions comprising said chimericnacid for the treatment of inflammatory disease. |
| priorityDate | 1999-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.