Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ef8acc27b4252e343aa5da877c870d2 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-153 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-28 |
filingDate |
1998-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee1df7bb3ff36a7f154bea04857b5fee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a047df6553f49dff999169b9947bdea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50912e13ac3d13f8dcc342f2bbd3dee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b0a038bb0d6e1407e0c316c0939ad1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e035b324a71717e489a653586fb0f66b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6a090f167c3eca809042b9e90ac728a |
publicationDate |
2000-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CZ-20001127-A3 |
titleOfInvention |
A method for producing unsymmetrical cyclic ureas through monoacylated diamine intermediates |
abstract |
The solution relates to an improved preparation processnunsymmetrical cyclic ureas of formula VIanalso intermediates in the preparation of unsymmetrical cyclicnureas. In this process, the diamine of formula I-a is selectivelynmonoacylated to give unsymmetrical monoacylatedndiamine, which can be converted to an unsymmetrical intermediate.nThis unsymmetrical intermediate can be further alkylated,ncyclize and / or modify to form compounds that arenuseful as HTV protease inhibitors for the treatment of HIV infection.nThe invention makes available the preparation of a number of asymmetric seriesncyclic ureas. |
priorityDate |
1998-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |