| abstract |
Compounds of formula (I) in which R<1> and R<2>, which may be the same or different, is each selected from hydrogen, halogen or C(1-8)alkyl; R<3> is aryl or arylC(1-4)alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; are inhibitors of the enzyme Lp-PLA2 and thereof of use in treating atherosclerosis. |