http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-172596-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ba174d8c5f519b36c907a0f979b7aec |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 1996-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_896226d18f4821895bf228d976ce23d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbf2c5fedc4c8f6cba9ce4775c1e3806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_977b5b08296458a35df66787b90166c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_508355f71a1650b268846e0e26477863 |
publicationDate | 1997-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CZ-172596-A3 |
titleOfInvention | PROCESS FOR PREPARING SUBSTITUTED HEXAHYDRO-2N-CYCLOPENTA/b/FURAN-2-ONES |
abstract | In the present invention there is disclosed a process for preparing substituted hexahydro-2H-cyclopenta/b/furan-2-ones of the general formula I, in which A represents hydrogen, B represents a hydroxyl group or A together with B form an ethylenedioxyl bridge, R represents alkyl containing 1 to 6 carbon atoms being optionally branched or a phenoxyl group being optionally substituted with a halogen or a haloalkyl group containing 1 to 2 carbon atoms in the alkyl moiety, particularly 3-chlorophenoxyl or 3-trifluoromethylphenoxyl group. The proposed preparation process is characterized by transesterification of starting lactone esters of the general formula II, in which A, B, R and Ph are as specified above in anhydrous methanol and in the presence of alkali metal alkyloxides as catalysts at a temperature ranging from 20 to 65 degC for a period of 1 to 6 hours, whereby after crystallization of methyl-p-phenyl benzoate the required hydroxy derivative of the general formula I in actually quantitative yield and high purity is obtained. |
priorityDate | 1996-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.