http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CZ-16393-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0cf138215aaf6cbd6ed8d8a34222134 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-08 |
| filingDate | 1993-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b02057645896a65decea4bc6ac81cd9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_911f1178a87e21f7a5c021b67355e607 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61f39257fa6e4094edd540a5cd34c0c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c98ef712beb878e3705441cbf5f1f89c |
| publicationDate | 1995-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CZ-16393-A3 |
| titleOfInvention | Process for preparing 3,14 beta-dihydroxy-17-cycloalkyl methylmorphinans |
| abstract | A process for preparing 3,14 beta-dihydroxy-17-cycloalkyl methylmorphinan of general formula I, above all Butorphanol, which is an effective analgesic. Synthesis includes single-stage alkylation of 3,14β-dihydroxy morphinan or 14β-hydroxy-3-methoxy morphinan by the relevant cycloalkyl methyl halogenide or acylation by cycloalkane carbonyl halogenide with subsequent reduction of the carbonyl group by the action of complex hydrides and possible cleavage of the essential functional group by the action of a complex aluminium halogenide - dialkyl sulphate.<IMAGE> |
| priorityDate | 1993-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.