| abstract |
Aminotriazole compounds substituted with a piperidinyl ring which is itself substituted with a heterocyclic ring are disclosed. These compounds are mammalian acid chitinase and chitotriosidase inhibitors. Also disclosed are methods of using the compounds in the treatment of allergen-induced asthma reactions, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurological diseases, metabolic diseases, liver diseases, cancer syndrome, polycystic ovary syndrome. |