| abstract |
The present invention relates to substituted phenyl-3-aza-bicyclo [3.1.0] hex-3-ylmethanes of general formula (I), in which R1, R2, R3, R4, R5 and R6 are as defined herein or salts thereof, preferably pharmaceutically acceptable salts thereof. The invention also relates to the production of said compounds, pharmacological compositions containing a compound according to the general formula (I), and the use of said compounds for the treatment of various diseases, such as diseases involving positive and negative symptoms of schizophrenia, as well as cognitive impairments. disorders related to schizophrenia, Alzheimer's disease and other neurological and psychiatric disorders. The compounds of the invention exhibit glycine transporter-1 (GlyT1) inhibitory properties. |