http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CY-1118674-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d3f1bfec8ac94cca9554e3c17db5c6d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0066 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 2016-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4acdaf988d09f161e8a734fbcc5c9e50 |
| publicationDate | 2017-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CY-1118674-T1 |
| titleOfInvention | PROCESSING FOR THE PRODUCTION OF OSTETROL |
| abstract | The present invention relates to a process for the preparation of a compound of formula (I), hydrates or solvates thereof; (I) said process comprises the steps of a) reacting a compound of formula (II) with an acylating or a silylating agent to produce a compound of formula (III), (II) (III) wherein P1 is a protecting group selected from R1CO-, or R2Si (R3) (R4) -, P2 is a protecting group which is selected from (R6R5R7) C-CO, or (R2) Si (R3) (R4) -, wherein R1 is a group selected from C1-6-alkyl or C3-6cycloalkyl; each group is optionally substituted with one or more substituents independently selected from fluoro or C1-4 alkyl; R2, R3 and R4 are each independently a group selected from C1-6alkyl or phenyl, each group optionally substituted with one or more independently selected from fluoro or C 1-4 alkyl; R 5 is a group selected from C 1-6 alkyl or phenyl; each group is optionally substituted with one or more substituents independently selected from fluoro or C 1-4 alkyl; and R6 and R7 are each independently hydrogen or a group selected from C1-6alkyl or phenyl, each group optionally substituted with one or more substituents independently selected from fluoro or C1-4alkyl; b) reaction of the compound of formula (III) in the presence of at least one oxidizing agent selected from permanganate, osmium oxide, hydrogen peroxide, or iodine and silver acetate to produce a compound of formula (IV); and (IV) 5 c) deprotection of its compound type (IV) for production a compound of formula (I). |
| priorityDate | 2011-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.