http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CY-1117007-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d958eff19f06ac6f6d931cc3a69ab126 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04 |
| filingDate | 2015-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed3ba16f27f8a8c6015c723bc4399487 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf7991cacfa819a8c47e40ec26d2e29a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5891659b29eebdd1cfd0bffb40536385 |
| publicationDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CY-1117007-T1 |
| titleOfInvention | PROCEDURES FOR THE PREPARATION OF FUNYLOCARBAMIDE ALINKLIES |
| abstract | The present invention relates to a process for preparing amino alkyl phenylcarbamate (4), comprising the steps of converting hydroxyphenyl ketone (2) to phenylcarbamate ketone (3), and converting phenylcarbamate ketone (3) to desired (4) ketone. Optionally the amino alkyl phenylcarbamate (4) can be broken down into its enantiomers and / or converted to a pharmaceutically acceptable acid by addition of a salt. The invention further relates to phenylcarbamate amino alkyls (4) and pharmaceutically acceptable salts prepared by the above process, in particular ribastigmine (1) and ribastigmic acid tartrate (9). Phenylcarbamate amino alkyls (4) may be included in pharmaceutical compositions. The invention further relates to a method of inhibiting acetylcholinesterase or treating dementia, senile dementia, Alzheimer's disease, Huntington's disease, late dyskinesia, hyperactivity, confusion disorder, ataxia, Down's disorder, mania or acute confusion disorder, using the phenylcarbamate amino alkyls (4) of the present invention. |
| priorityDate | 2003-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.