| abstract |
The purpose of the present invention is to find a therapeutic and / or prophylactic agent for gastrointestinal disorders and so on, wherein said agent has excellent activity and high safety. A compound represented by the general formula (I) or a pharmacologically acceptable salt thereof. In general formula (I): A represents an optionally substituted phenylene group; B represents an optionally substituted 4- to 10-membered heterocyclic group, an optionally substituted C6-10 aryl group or an optionally substituted C3-10 represents a hydrogen atom or a C1-3 alkyl group; R2 represents a hydrogen atom or a C1-3 alkyl group; R3 represents a C1-6 alkyl group, a C3-10 cycloalkyl group, a C1-3 alkoxy C1-3 alkyl group or a C1 -3-hydroxyalkyl; R4 represents a hydrogen atom or a C 1-6 alkyl group or a halogen atom; n is an integer from 1 to 4; and X represents methylene, -O-, -NH-, -N (C1-3 alkyl) -, C (= O) - , -S-, -S (O) -, -S (O2) - or a single bond. |