| abstract |
The invention relates to cis-tetrahydro-spiro (cyclohexane-1,1'-pyrido [3,4-b] indole) -4-amine derivatives, which act on the nosileptin / ORL-1 receptor system and - opioids and are characterized in particular by a selective activity in the treatment of chronic pain (including inflammatory pain, visceral pain, cancer pain, preferably neuropathic pain), without at the same time unfolding modulatory activity, |