| abstract |
Compounds of general formula (I) wherein W is a chloro or fluoro group; R1 is phenyl optionally substituted with one or more substituents selected from halogen, -CN, -C1-C6 alkyl, -SOR3, -SO2R3, -SO2N (R2 ) 2, -N (R2) 2, -NR2C (O) R3, -CO2R2, -CONR2R3, -NO2, -OR2, -SR2, -O (CH2) pOR2, and -O (CH2) pO (CH2) qOR2 wherein each R 2 is independently hydrogen, -C 1 -C 6 alkyl, -C 3 -C 8 cycloalkyl, aryl or heteroaryl; each R 3 is independently -C 1 -C 6 alkyl, -C 3 -C 8 cycloalkyl, aryl or heteroaryl; p and q are each independent numbers from 1 to 3; and the pharmaceutically acceptable salts, hydrates complex automatically, solvates, complexes or prodrugs are useful (a) orally administrable form of compositions for treating allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. |