| abstract |
The present invention relates to novel, water-soluble pharmaceutically acceptable crystalline addition salts (i) of an amine containing one or more hydroxyl and / or carboxyl groups with (ii) aminonicotinic acid derivatives of formula (I), wherein Ra, R, R, Rd independently represent each of the groups selected from hydrogen atoms, halogen atoms, C 1-4 alkyl groups which may be optionally substituted with 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and alkoxy groups C 1-4 They are optionally substituted with 1, 2 or 3 substituents selected from halogen atoms and hydroxy groups, and pharmaceutically acceptable solvates thereof. |