| abstract |
The present invention relates to alkylcyclohexyl ethers of dihydrotetraazabenzoazoylene derivatives, i.e., 5,6-dihydro-4H-2,3,5,10b-tetraza-benzo [e] azulene derivatives of alkylcyclohexyl ethyl derivatives of formula (I), wherein R is R, as described herein. The compounds according to the invention act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active substances of the present invention are useful as therapeutic agents that act peripherally and centrally in disorders of dysmenorrhea, sexual dysfunction in men and women, hypertension, chronic heart failure, inappropriate vasopressin secretion, cirrhosis, cirrhosis. , disorders in the spectrum of autism, schizophrenia and aggressive behavior. |