| abstract |
[PROBLEMS] The delivery of a novel dicycloester ester having excellent DPP-IV inhibitory activity or a pharmacologically acceptable salt thereof. [MEDIATION FOR SOLVING PROBLEMS] A new bicycloester derivative of the general formula: (1) or a pharmacologically acceptable salt thereof is provided (for example, (2S, 4S) -1 - [[N- (4-ethoxycarbonyl- .2] oct-1-yl) amino] acetyl] -4-fluoropyrrolidine-2-carbonitrile). |