http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CY-1112164-T1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c539db959cc0106cab1662303f94fce |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-513 |
| filingDate | 2011-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75fc18022cd204fabd69e024fa82748e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9ab13c7ebe19d1f4350727fa993a30f |
| publicationDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CY-1112164-T1 |
| titleOfInvention | PRODUCTS 1- [2'-3'-DIDOEXY-3'-C- (HYDROXYMETHYL) -BETA-D-RED-PENTOFURANOSYL] CYTOSIN AS INHIBITORS TOY HIV |
| abstract | Compounds of formula (I) wherein: R1 is independently H1-OR3, -NHR4 ∙ C1-C4 alkyl ∙ or, when n is 2, together with adjacent R1 defines an olefin bond ic; R2 is H ∙ or when the twin pair R1 is C1-C4 alkyl, this R2 may be C1-C4 alkyl, or when the twin pair R1 is -OR3, this R2 may also be -C (= O) OH or any of the pharmaceutically an ester thereof; R3 is independently H, or a pharmaceutically acceptable ester thereof; R4 is independently H or a pharmaceutically acceptable amide thereof; R5 and R6 are H or an the amine prodrug moiety n is 1, 2, or 3; and the pharmaceutically acceptable salts thereof; and have utility in the treatment or prophylaxis of HIV, in particular reverse transcriptase mutants which allow for a nucleoside or nucleoside phosphate binding cut from the hatching DNA strand through ATP-mediated or pyrophosphate-mediated resection. |
| priorityDate | 2005-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.