http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CY-1109669-T1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437
filingDate 2009-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a316a3cdee31f948c00ba7b4366e97dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86f7b5c992833dd7c685bd98f26012c
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publicationDate 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CY-1109669-T1
titleOfInvention USE OF SUBSTITUTED INDOLISIN 1,2,3 PRODUCERS FOR MEDICAL TREATMENT RELATED TO A PATHOLOGICAL CHORIOID VASCULATION
abstract The present invention relates to the use of substituted indolizine derivatives 1, 2, 3 for the manufacture of medicaments useful in the treatment of diseases related to a pathological choroid angiogenesis, which derivatives correspond to the following general formula (I): in which R1 represents -OH, alkoxy (C1-C5), carboxy, alkoxycarbonyl (C2 -C6), -NR5R6, -NH-SO2-Alk, -NH-SO2Ph, -NH-CO-Ph, -N (Alk) -CO-Ph , -NH-CO-NH-Ph, -NH-CO-Alk, -NH-CO2-Alk, -O- (CH2) n -cAlk, -O-Alk-COOR7, -O-Alk-O-R8, -O-Alk-OH, -O-Alk-C (NH2): NOH, -O-Alk-NR5R6, -O-Alk-CN, -O- (CH2) n-Ph, -O-Alk-CO- NR5R6, -CO-NH- (CH2) m-COOR7, -CO-NH-Alk; R2 represents H, alkyl (C1-C5), alkyl halide (C1-C5), cycloalkyl (C3-C6) or optionally substituted phenyl; A represents -CO-, -SO-, or -SO2-, R3 and R4 are identical or otherwise represent each individually H, alkoxy (C1 -C5), amino, carboxy, alkoxycarbonyl (C2-C6), -OH, nitro, hydroxyamino, -Alk-COOR7, -NR5R6, -NH-Alk-COOR7, -NH-COO-Alk, -N (R11) - SO2-Alk-NR9R10, -N (R11) -SO2-Alk, -N (R11) -Alk-NR5R6, -N (R11) -CO-Alk-NR9R10, -N (R11) -CO-Alk, -N (R11) -CO-CF3, -NH-Alk-HetN, -O-Alk-NR9R10, -O-Alk-CO-NR5R6, -O-Alk-HetN, or R3 and R4 together form an unsaturated heterocycle consisting of 5 to 6 chains, optionally in the form of one of their pharmaceutically acceptable salts.
priorityDate 2004-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 29.