| abstract |
New multifunctional compound to treat or slow down neurodegenerative diseases e.g. Alzheimer's disease and related pathologies. Formula (I), wherein, R is a non-steroidal anti-inflammatory drug group selected from the category of acetic acid derivatives (such as indomethacin), propionic acid derivatives (e.g. naproxen, ketoprofen) or various other acids anti-inflammatory activity which does not belong to the above mentioned categories, A is a CHOH or CH2 or (CH2) 2 group, Y is an antioxidant group (cysteamine or cysteine ethyl ester) or a neuroprotective group (2-pyridin-3-yl-alkan) or NGF-inducing group (e.g. 2-methoxy-4-methylphenol). |