abstract |
Slow-release tablet consisting of at least two layers, characterized in that at least one layer immediately releases the drug 1S, 9S (RS, 3S) N- (2-ethoxy-5-oxo-tetrafuran-3-yl) -6 , 10-dioxo-9- (isoquinoline-1-yl-amino) -1,2,3,4,7,8,9,10-octahydro-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxamide and / or its salts or derivatives and / or free acids thereof, and that at least one layer delays the release of the drug IS, 9S (RS, 3S) N- (2-ethoxy-5) -oxo-tetraphuran-3-yl) -6,10-dioxo-9- (isoquinolin-1-yl-amino) -1,2, 3,4,7,8,9,10-octahydro-6H-pyridazino [1,2-a] [1,2] diazepine-1-carboxamide and / or its salts or derivatives and / or free acids thereof for the treatment of autoimmune diseases, type I and type II diabetes, rheumatoid arthritis, osteoarthritis and / or psoriasis. |