| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_66996dcf2dc59f595b8c0584986d50b3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-3221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00166
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-32213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F25-43141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F25-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F5-06 |
| filingDate |
2009-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71c7bee0e84cd19066b957b7c91f1cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_573efe1ffef4d0d06a208061a5147fb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e127f2a586b4f98ffe1edea03b341ba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe728927d0584b93b8fa73152235d1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41b332e631850977a9557661970b6801
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fad80b80be68ae4a9db113dbd60bc345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67c2da6340a1e126fa257de9eaffa698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17233dcdd569e18c6278f7f30bec4dfb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed21b35552a1b60f385237dcf8da6f15 |
| publicationDate |
2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CY-1108812-T1 |
| titleOfInvention |
PROCEDURES FOR THE PRODUCTION OF AMINO - PROTECTED PRODUCERS OF 4-AMINOMYTHYLENE-PYRROLIDIN-3-ONE, GEMIFLOXAKINIS OR A SAL |
| abstract |
The invention provides a process for the preparation of a compound of formula (I): wherein R1 and R2 which may be the same or different are amino protecting groups, which process comprises protecting a compound of formula (II) by continuous method operation in solution phase. This offers advantages over batch operation. The process is usually carried out on reaction equipment configured for use in a continuous process method, for example comprising one or more static mixers or a plunger flow reactor. Preferably, the plunger reactor comprises a laminated tubular reactor fitted internally with intermixing elements which continuously separate and re-mix the reaction currents by enhancing mass and heat transfer, thereby achieving a uniform plunger flow profile. The invention also provides a process for the preparation of the antibacterial compound gemifloxacin or a pharmaceutically acceptable salt and / or hydrate thereof, comprising converting a compound of formula (I). The invention also provides a process for the preparation of a compound of formula (VIIIa). |
| priorityDate |
2001-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |