| abstract |
Compound corresponding to general formula (I): R 1 represents a C 1-6 alkyl substituted, a C 3-7 -cycloalkyl, a thiophene, a benzothiophene, a pyridinyl, a furanyl or a phenyl; the phenyl groups are; R2 and R2 'represent independently of one another a hydrogen atom, a halogen atom, a hydroxy, a C1-3 alkoxy, a C1-3 alkyl, a C3-7 cycloalkyl, a C-C (O) group -C1-6 alkyl, or R2 and R2 'form an oxo group; R3 represents a hydrogen atom or a C1-6 alkyl having a substituent from a hydroxy or C1-3 alkoxy; R4 and R5 represent, independently of one another a hydrogen atom, a substituted C1-7 alkyl, a C3-7 cycloalkyl, a phenyl, a naphthyl or one - C (X) R6; the C3-7 cycloalkyl and phenyl groups are substituted; provided that at least one group R4 or R5 represents a group - C (X) R6; X represents an oxygen atom or a sulfur atom; R6 represents a C1-6 alkoxy group, a hydroxy or a group - NR7R8; the C1-6 alkoxy group is substituted by a phenyl; R7 and R8 are substituted represent, independently of one another a hydrogen atom, a substituted C1-6 alkyl group, a C3-7 cycloalkyl, a C1-6 alkoxy or a phenyl; or R7 and R8 together with its atom the nitrogen bearing them form a cycle of aziridine, azetidine, pyrrolidine, piperidine or morpholine; the C3-7 cycloalkyl and phenyl groups are substituted; as a base, an addition salt to an acid, a hydrate or a solvent in a acid. Application to treatment. |